Abstracts ASN Report 2019

effects and reduce the probabilities of cancers arising from exposure to ionising radiation, which are also known as radiation- induced (or radio-induced) cancers; the results of the studies as a whole seem to indicate that radiation-induced cancers represent the predominant health risk associated with exposure to ionising radiation. ׏ِ א ɀɀƺɀɀȅƺȇɎ Ȓǔ Ɏǝƺ ȸǣɀǸɀ ƏɀɀȒƬǣƏɎƺƳ ɯǣɎǝ ǣȒȇǣɀǣȇǕ ȸƏƳǣƏɎǣȒȇ Ļĸ ŀłŁļŇłŅļŁĺ łĹ ĶĴŁĶĸŅ ĸŃļķĸŀļłĿłĺŌ ļŁ ŅĴŁĶĸ ļņ ĵĴņĸķ łŁ disease registries, on the monitoring of causes of death and also, more recently, on the utilisation of data from the Medicalised Programme for Information Systems (PMSI) of healthcare facilities and the Long-Term Disease (LTD) notifications. The registries are structures that provide “ a continuous and exhaustive collection of nominative data concerning one or more health events in a geographically defined population, for purposes of research and public health, managed by a team with the appropriate skills ”. At ŃŅĸņĸŁŇ ŇĻĸŅĸ ĴŅĸ ӆӅׇĶĴŁĶĸŅ ŅĸĺļņŇŅļĸņ ļŁ ŅĴŁĶĸє łŀĸ ĴŅĸ ѢĺĸŁĸŅĴĿ registers”, concerning all types of cancer and covering one département (2) or more; others are “specialised registers”, focusing 2. Administrative region headed by a Prefect. on a particular type of cancer. Their geographical perimeter can vary (town, département , region, or even nationwide). Of the three national registers, one concerns pleural mesothelioma, primarily in the context of exposure to asbestos fibres, while the other two cover all the cancerous pathologies in the child and adolescent ňŃ Ňł ӄӋׇŌĸĴŅņ łĹ Ĵĺĸ ҎņłňŅĶĸѓ Ĵҏє The aim of the register for a given area is to highlight differences in spatial distribution, to reveal changes over time in terms of increased or reduced rate of incidence in the different cancer locations, or to identify clusters of cases. Some registers, depending on the quality of their population database and their age, are used in numerous studies exploring cancer risk factors (including environmental risks). However, the registers do not necessarily cover the areas close to nuclear installations. Epidemiological investigation is complementary to monitoring. Its purpose is to highlight an association between a risk factor and the occurrence of a disease, between a possible cause and an effect, or at least to enable such a causal relation to be asserted with a very high degree of probability. The intrinsic 69 01 74 73 38 05 26 07 42 04 06 83 13 84 2B 2A 30 48 34 11 66 09 31 65 64 40 32 82 81 12 46 47 33 24 19 15 43 63 03 23 87 16 17 85 79 86 36 18 58 71 39 25 21 70 90 68 88 52 89 45 41 37 49 44 56 29 22 35 50 53 72 61 14 27 28 76 80 60 62 59 02 77 91 78 95 93 94 92 75 51 08 10 55 54 57 67 Guadeloupe Martinique La Réunion Guyane Nouvelle-Calédonie General registry of tumours Specialised registry: (e.g. registry of cancers of the thyroid and the digestive tract, registry of haematological malignancies) including 3 national registries – Registry of solid tumours in children – Registry of haematological malignancies in children – National multicentric registry of mesothelioma The various cancer registries in France (2018) ASN Report on the state of nuclear safety and radiation protection in France in 2019 99 ׎׏ ٲ NUCLEAR ACTIVITIES: IONISING RADIATION AND HEALTH AND ENVIRONMENTAL RISKS 01