SHEET INTERNAL CONTAMINATION MEASUREMENTS AND TREATMENTS Specific antidotes 39 Ca-DTPA Pentetate calcium trisodium PRESENTATION Ca-DTPA 250 mg/ml, injectable solution. Vial of 4 ml, i.e. 1 g of a 25% solution of Ca-DTPA (Central Pharmacy of the Armed Forces). INDICATIONS Internal contamination (ingestion, inhalation, wound): Americium (RH4), Californium (RH12), Cerium (RH13), Chromium (RH14), Cobalt (RH15), Curium (RH17), Erbium (RH18), Europium (RH19), Indium (RH23), Iridium (RH25), Iron (RH26), Lanthanum (RH27), Lutetium (RH29), Manganese (RH30), mixture of fission products (RH31), Plutonium (RH36), Praseodymium (RH39), Prometheum (RH40), Ruthenium (RH42), Samarium (RH43), Scandium (RH44), Thorium (RH52), Ytterbium (RH55), Yttrium (RH56), Zinc (RH57), Zirconium (RH58). DOSAGE • Adults – Children > 12 years: slow IV injection or infusion in 15 min of a half-vial of Ca-DTPA (i.e. 0.5 g), diluted in 100 to 200 ml of saline isotonic solution or 5% glucose solution, without exceeding 1 g/d. • Children of 2 to 12 years: slow IV injection or infusion 14 mg/kg, without exceeding 0.5 g/d. TREATMENTS COMPLEMENTARY TO INTRAVENOUS ADMINISTRATION Pulmonary contamination: • Adults – Children (to be used with caution): 1 g in a single administration by inhalation by nebulisation only (spray mist, 50/50 dilution of a 4 ml vial in sterile or saline water). Contaminated wounds: Pour one or more vials over the wound. CONTRAINDICATIONS None at the recommended dosage. Manufactured by the Central Pharmacy of the Armed Forces (PCA) and available, subject to conditions, from the Directorate of Health Product Procurements for the Armed Forces (DAPSA-Orléans). 1% iodine solution (Lugol's iodine) PRESENTATION LUGOL's iodine (1% potassium iodide – iodine solution) oral drops, prepared by pharmacist. INDICATIONS Internal contamination (ingestion, inhalation, wound) by iodides (RH24) and radioactive tellurium (RH31 and RH50). Lugol's iodine can be used as an alternative to potassium iodide tablets when the latter are not available. It can also be used for skin contamination, after washing with mild soap and water as th 1st line treatment. DOSAGE • Adults – Children > 12 years: 80 drops. • Children of 3 to 12 years: 40 drops. • Children < 3 years: 20 drops (Codex dropper). MEDICAL RESPONSE IN NUCLEAR OR RADIOLOGICAL EMERGENCY 113
RkJQdWJsaXNoZXIy NjQ0NzU=