french-nuclear-safety.fr/dosimetric-references EMERGENCY TREATMENT FIRST-LINE TREATMENT Succimer PRESENTATION SUCCICAPTAL® 100 mg capsules (SERB). DOSAGE Children (2 to 11 years), adolescents (12 to 17 years), adults: 10 mg/kg to be administered orally every 8 h (i.e. 30 mg/kg/d). In the adult, the dose of 1.80 g/d should generally not be exceeded. With children (< 6 years), the capsules can be opened (to ensure the right dosage) and the powder dissolved in a fruit compote, yoghurt or a drink in order to mask its unpleasant taste and smell. SECOND-LINE TREATMENT Only to be administered if Succimer cannot be used. Dimercaprol PRESENTATION B.A.L. solution for intramuscular injection (SERB). 2 ml vials containing 200 mg. DOSAGE 3 mg/kg body weight and strictly by IM injection, 1 injection every 4 h. As with all non-aqueous injectable solutions, administer using a glass syringe. CONTRAINDICATIONS ▖Special warning in case of renal impairment. ▖Allergy to peanuts. PHYSICAL CHARACTERISTICS Antimony-122 ( 122Sb ) ▖Radioactive half-life: 2.7 d ▖Main types of radiation emitted: b- and g Antimony-124 ( 124Sb ) ▖Radioactive half-life: 60.2 d ▖Main types of radiation emitted: b- and g Antimony-125 ( 125Sb ) ▖Radioactive half-life: 2.7 years ▖Main types of radiation emitted: b- and g SOURCES OF EXPOSURE ▖Nuclear reactors (activation products) 125 Sb Antimony 124 Sb Antimony 122 Sb Antimony INTERNAL CONTAMINATION MEASUREMENT J Urine bioassay J Faeces bioassay J In vivo measurement Antimony EXPOSURE RISK ▖Irradiation ++ ▖External contamination ++ ▖Internal contamination +++ DOSE COEFFICIENT REFERENCE Effective committed dose per becquerel incorporated, taken from the Order mentioned in Article R. 1333-24 of the Public Health Code: RADIONUCLIDE HANDBOOK • Emergency treatment of internal contamination RH 5
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