PHYSICAL CHARACTERISTICS Arsenic-76 ( 76As ) ▖Radioactive half-life: 1.1 d ▖Main types of radiation emitted: b- and g SOURCES OF EXPOSURE ▖Laboratories 76 As Arsenic EXPOSURE RISK ▖Irradiation ++ ▖External contamination ++ ▖Internal contamination ++ Arsenic EMERGENCY TREATMENT FIRST-LINE TREATMENT Succimer PRESENTATION SUCCICAPTAL® 100 mg capsules (SERB). DOSAGE Children (2 to 11 years), adolescents (12 to 17 years), adults: 10 mg/kg to be administered orally every 8 h (i.e. 30 mg/kg/d). In the adult, the dose of 1.80 g/d should generally not be exceeded. With children (< 6 years), the capsules can be opened (to ensure the right dosage) and the powder dissolved in a fruit compote, yoghurt or a drink in order to mask its unpleasant taste and smell. SECOND-LINE TREATMENT Only to be administered if Succimer cannot be used. Dimercaprol PRESENTATION B.A.L. solution for intramuscular injection (SERB). 2 ml vials containing 200 mg. DOSAGE 3 mg/kg body weight and strictly by IM injection, 1 injection every 4 h. As with all non-aqueous injectable solutions, administer using a glass syringe. CONTRAINDICATIONS ▖Special warning in case of renal impairment. ▖Allergy to peanuts. INTERNAL CONTAMINATION MEASUREMENT J Urine bioassay J Faeces bioassay J In vivo measurement french-nuclear-safety.fr/dosimetric-references DOSE COEFFICIENT REFERENCE Effective committed dose per becquerel incorporated, taken from the Order mentioned in Article R. 1333-24 of the Public Health Code: RADIONUCLIDE HANDBOOK • Emergency treatment of internal contamination RH 6
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