Medical response in a nuclear or radiological emergency

PHYSICAL CHARACTERISTICS Lead-210 ( 210Pb ) ▖Radioactive half-life: 22.2 years ▖Main types of radiation emitted: a (very low level), b- and X SOURCES OF EXPOSURE ▖210Pb: decay product of Uranium-238 210 Pb Lead EXPOSURE RISK ▖Irradiation ++ ▖External contamination ++ ▖Internal contamination ++ INTERNAL CONTAMINATION MEASUREMENT J Urine bioassay J Faeces bioassay Lead EMERGENCY TREATMENT Two treatments are possible. The use of Succimer is recommended for children. Sodium calcium edetate PRESENTATION SODIUM CALCIUM EDETATE SERB®, 50 mg/ml, solution for IV injection. 10 ml vials containing 500 mg of Sodium calcium edetate. DOSAGE Adults: 2 vials by infusion in 250 ml of saline. Children according to their weight (as a guideline only): Weight Daily dosage < 18 kg ½ vial 18 to 30 kg ½ vial to 1 vial ≥ 30 kg 1 vial Succimer PRESENTATION SUCCICAPTAL® 100 mg capsules (SERB). DOSAGE Children (2 to 11 years), adolescents (12 to 17 years), adults: 10 mg/kg to be administered orally every 8 h (i.e. 30 mg/kg/d). In the adult, the dose of 1.80 g/d should generally not be exceeded. With children (< 6 years), the capsules can be opened (to ensure the right dosage) and the powder dissolved in a fruit compote, yoghurt or a drink in order to mask its unpleasant taste and smell. french-nuclear-safety.fr/dosimetric-references DOSE COEFFICIENT REFERENCE Effective committed dose per becquerel incorporated, taken from the Order mentioned in Article R. 1333-24 of the Public Health Code: RADIONUCLIDE HANDBOOK • Emergency treatment of internal contamination RH 28

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