french-nuclear-safety.fr/dosimetric-references PHYSICAL CHARACTERISTICS Silver-110m ( 110mAg ) ▖Radioactive half-life: 250 d ▖Main types of radiation emitted: g Silver-111 ( 111Ag ) ▖Radioactive half-life: 7.5 d ▖Main types of radiation emitted: bSOURCES OF EXPOSURE ▖110mAg: nuclear reactors 111 Ag Silver 110m Ag Silver INTERNAL CONTAMINATION MEASUREMENT J Urine bioassay J Faeces bioassay J In vivo measurement Silver EMERGENCY TREATMENT Two treatments are possible. Sodium chloride PRESENTATION LAVOISIER SODIUM CHLORIDE 0.9% infusion solution. INDICATIONS Contamination by ingestion, to limit the absorption of silver by inducing its precipitation (as Silver chloride). DOSAGE 100 ml of saline (0.9% Sodium chloride solution) by oral route. Penicillamine PRESENTATION TROLOVOL® (ERENPHARMA), tablet containing 0.3 g of Penicillamine. DOSAGE Adults: 3 to 5 tablets per day in 2 to 3 doses. Children: 20 mg/kg /d of body weight, divided into 2 or 3 doses. CONTRAINDICATIONS ▖Haematuric and protein nephropathies. ▖Severe haematological disorders. ▖Lupus erythematosus, myasthenia gravis, severe dermatoses. ▖Allergy to penicillins and cephalosporins, due to the possibility in certain people of cross-allergenicity between the beta-lactamines and D-penicillamine. ▖History of severe accidents (medullar aplasia, pemphigus, myasthenia gravis) caused by thiol derivatives (tiopronine, pyritinol). DOSE COEFFICIENT REFERENCE Effective committed dose per becquerel incorporated, taken from the Order mentioned in Article R. 1333-24 of the Public Health Code: EXPOSURE RISK ▖Irradiation ++ 110mAg ▖External contamination +++ 110mAg and 111Ag ▖Internal contamination ++ 110mAg RADIONUCLIDE HANDBOOK • Emergency treatment of internal contamination RH 45
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