Medical response in a nuclear or radiological emergency

french-nuclear-safety.fr/dosimetric-references PHYSICAL CHARACTERISTICS Sodium-22 ( 22Na ) ▖Radioactive half-life: 2.6 years ▖Main types of radiation emitted: b+ and g Sodium-24 ( 24Na ) ▖Radioactive half-life: 15 h ▖Main types of radiation emitted: b- and g In the event of a criticality accident, the Sodium (Na) present in the organism is partly activated as Sodium-24 (24Na). SOURCES OF EXPOSURE ▖Nuclear medicine ▖Research laboratories 24 Na Sodium 22 Na Sodium INTERNAL CONTAMINATION MEASUREMENT J Urine bioassay J In vivo measurement Sodium EMERGENCY TREATMENT Sodium chloride PRESENTATION LAVOISIER HYPERTONIC SODIUM CHLORIDE 10%, ampoule 20 ml vial, 10 g for 100 ml of Sodium chloride solution. INDICATION Internal contamination by ingestion. DOSAGE To be administered by oral route: Weight Dosage Quantity of sodium in mmol/kg 0 to 10 kg 3 vials 8 10 to 20 kg 6 vials 8 20 to 30 kg 9 vials 8 30 to 40 kg 12 vials 8 40 to 50 kg 13 vials 7 > 50 kg 14 vials 8 Risk of hypernatremia if more than 8 mmol/kg of sodium is administered. The dosage is valid for vials containing 20 ml of 10% Sodium chloride. Other formats are sold in the form of: ▖LAVOISIER SODIUM CHLORIDE 20% (0.10 g/ml), 1 vial of 10 ml: the dosage remains the same. ▖LAVOISIER SODIUM CHLORIDE 20% (0.10 g/ml), 1 vial of 20 ml: the dosage must be reduced by 2 (halved). CONTRAINDICATIONS ▖Hypernatremia. ▖Hyperchloremia. ▖Severe cases of overhydration and fluid retention, particularly in case of decompensated heart failure or decompensated liver failure (ascetic oedematous syndrome in liver cirrhosis), of pre-eclampsia/ eclampsia. DOSE COEFFICIENT REFERENCE Effective committed dose per becquerel incorporated, taken from the Order mentioned in Article R. 1333-24 of the Public Health Code: EXPOSURE RISK ▖Irradiation ++ ▖External contamination + ▖Internal contamination ++ RADIONUCLIDE HANDBOOK • Emergency treatment of internal contamination RH 46

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